VITAMIN B12[CYANOCOBALAMIN] INJ 1000MCG/ML (10ML)

Generic Name: cyanocobalamin
Brand Name: Vitamin B12
Drug class: Vitamins

The generic Cyanocobalamin is available in the forms & strengths of: 10 ml vial (1000 mcg/ml), 30 ml vial (1000 mcg/ml), and 5 x 1ml Ampoule (1000 mcg/ml) to be given subcutaneously (into skin fat), intramuscularly (into muscles), or intravenously (into veins). It is also available in various other forms, including chewable tablets and gummies, capsules, tablets, powders, strips, drops, and liquids.

Vitamin B12 is important in maintaining overall good health. It helps the body to form red blood cells and to metabolize carbohydrates, fats, and proteins. It is important for the proper function and development of the brain and nerves. Cyanocobalamin is a man-made form of Vitamin B12 used to treat vitamin B12 deficiency in people with pernicious anemia and various other conditions.

At doses at or above the recommended dietary allowance (RDA), vitamin B12 supplementation is highly effective for preventing and treating vitamin B12 deficiency and associated diseases such as pernicious anemia (a type of anemia due to vitamin B12 deficiency). Some people may have low vitamin B12 levels because of absorption problems or inadequate amounts in their diet (for example, vegetarians are at risk since vitamin B12 is available only from animal food sources). Vitamin B12 supplementation in these cases can help prevent vitamin B12 deficiency.

Vitamin B12 has also been studied to prevent heart diseases and to treat Alzheimer’s disease, memory loss, male infertility, diabetes, mental disorders, inflammatory bowel disease, asthma, fatigue, and high cholesterol. However, there is not enough reliable evidence for these uses; additional studies are required to confirm the benefits of vitamin B12 in these conditions.

Vitamin B12 has also been studied together with folic acid and vitamin B6 for prevention of recurrent strokes and breast cancer. However, research has shown that this combination of supplements did not lower the risk of stroke or breast cancer.

Your health care provider may have recommended this product for other conditions. Contact a health care provider if you have questions.

Recommended not take Vitamin B12 if you:

• vitamin B12 is generally well tolerated by most people if taken in recommended amounts. Vitamin B12 from food sources can interact with certain medications, including proton pump inhibitors (e.g., omeprazole, pantoprazole), H2 blockers (e.g., famotidine, ranitidine), and metformin. These can affect the absorption of dietary B12 into the body, though this does not appear to be a problem with supplements

• heavy drinking for more than 2 weeks can also decrease vitamin B12 absorption

• are on chloramphenicol (an antibiotic) since chloramphenicol can destroy the newly produced blood cells that vitamin B12 helped to make

• are on vitamin C and/or potassium supplements as they can decrease the effects of vitamin B12. It is not known whether this interaction is clinically significant or not. You can avoid this by separating the vitamins and taking them at least 2 hours apart. Consult your health care provider for more information on drug interactions

Before taking any new medications, including natural health products, speak to your physician, pharmacist, or other health care provider. Tell your health care provider about any natural health products you may be taking.

Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.

Inform your doctor about all prescription, over-the-counter (non-prescription), and herbal medications that you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.

This is not a complete list of possible side effects. If you notice other effects not listed, please contact your doctor or pharmacist.

Possible side effects include:

• mild diarrhea

• itching or redness at the injection site

• feeling of swelling all over the body

• chest pain or short of breath

• irregular heartbeat or heart failure

• low potassium levels in the blood (hypokalemia)

• muscle cramps

• unusual weakness or tiredness

© 2023 Arcedpharmas is the registered trademark used under license from YYOUNG Trademark Ltd. All material copyright MediResource Inc. 1996 – 2023. Terms and conditions of use. The contents herein are for informational purposes only. Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional.

CRESTOR 40MG BLSPK  (30 TABLETS)

Generic Name: rosuvastatin
Brand Name: Crestor
Drug class: HMG-CoA Reductase Inhibitors, Lipid-Lowering Agents, Statins

WHAT IS THE DOSAGE OF THIS MEDICATION?

Crestor and its generic rosuvastatin is available in the strength of 5 mg, 10 mg, 20 mg, and 40 mg tablets.

WHAT IS THIS MEDICATION USED FOR?

Rosuvastatin belongs to the group of medications known as HMG CoA reductase inhibitors ("statins"). It is used, along with a healthy diet and exercise program, to improve cholesterol levels by decreasing low-density lipoprotein (LDL) cholesterol ('bad cholesterol') and triglycerides in the blood, and increasing high-density lipoprotein (HDL) cholesterol ('good cholesterol') in the blood. It is also used to treat people who have certain inherited cholesterol disorders.

Rosuvastatin works by blocking the enzyme that helps make cholesterol in the body. People with high blood cholesterol levels have a higher risk of heart diseases such as heart attacks. When cholesterol levels are lowered with a combination of medication, diet, and exercise, the risk of heart disease is lowered. It takes 2 to 4 weeks to see the maximum effect of this medication on cholesterol levels in blood tests.

It can also be used to reduce the risk of heart attacks, stroke, and angioplasty for people who have at least 2 risk factors for cardiovascular disease.

Before starting rosuvastatin, you should be following a cholesterol-lowering diet. If appropriate, a program of weight control and physical exercise should also be implemented.

The recommended dose of rosuvastatin ranges between 5 mg and 40 mg once daily. For most people, the usual recommended starting dose of rosuvastatin is 10 mg once daily. If necessary, the dose may be increased to a maximum of 40 mg daily. People who require the maximum dose of 40 mg per day should consult a specialist.

For children 10 to 17 years of age, who have inherited cholesterol disorders, the recommended starting dose is 5 mg taken once daily. Your doctor may increase this dose to a maximum of 10 mg daily, depending on the effectiveness of the medication and how well it is tolerated.

For people with severely reduced liver function, the maximum daily dose is 20 mg.

For people with severely reduced kidney function, the starting dose should be 5 mg daily and the maximum daily dose is 10 mg.

A starting dose of 5 mg daily is recommended for people of Asian descent (Chinese, Filipino, Japanese, Korean, Vietnamese, or Asian-Indian origin) and those who have severe kidney problems. This low dose should also be considered for people who do not need aggressive cholesterol-lowering effects and for people who may be at a greater risk of experiencing muscle-related problems.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

Rosuvastatin may be taken in the morning or in the evening, with or without food.

It is very important that this medication be taken exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and carry on with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store this medication at room temperature, protect it from light and moisture, and keep it out of the reach of children. Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

WHO SHOULD NOT TAKE THIS MEDICATION

Do not take rosuvastatin if you:

• are allergic to rosuvastatin or any ingredients of the medication

• are pregnant

• are breast-feeding

• are taking cyclosporine

• are taking the medications sofosbuvir/velpatasvir/voxilaprevir for chronic hepatitis C virus infection

• have active liver disease or have unexplained increases in certain liver function tests

Do not take the 40 mg strength of rosuvastatin if you:

• are of Asian descent (Chinese, Filipino, Japanese, Korean, Vietnamese, or Asian-Indian origin)

• are taking niacin or a fibrate (e.g., gemfibrozil, fenofibrate)

• have alcoholism or consume large quantities of alcohol

• have an inherited muscle disorder or a family history of these disorders

• have had muscle damage with another statin medication (e.g., lovastatin, pravastatin, simvastatin)

• have hypothyroidism (an underactive thyroid gland)

• have other medical conditions or are taking other medications that would increase blood levels of rosuvastatin (check with your doctor or pharmacist to see if this applies to you)

• have severely reduced liver or kidney function

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POTENTIAL INTERACTION WITH OTHER MEDICATION

The following medications could potentially interact with rosuvastatin:

• antacids (if taken within 2 hours of taking rosuvastatin) (e.g., aluminum hydroxide, calcium carbonate, magnesium hydroxide)

• apalutamide

• bezafibrate

• carbamazepine

• clopidogrel

• cobicistat

• colchicine

• cyclosporine

• dronedarone

• elagolix

• eltrombopag

• eslicarbazepine

• fenofibrate

• gemfibrozil

• hepatitis C antivirals (e.g., glecaprevir and pibrentasvir, grazoprevir, ledipasvir, sofosbuvir, velpatasvir, voxilaprevir)

• HIV protease inhibitors (e.g., atazanavir, indinavir, ritonavir, saquinavir)

• itraconazole

• letermovir

• niacin (nicotinic acid)

• niacinamide

• pazopanib

• raltegravir

• regorafenib

• repaglinide

• rifampin

• other "statin" anti-cholesterol medications (e.g., atorvastatin, lovastatin, simvastatin)

• teriflunomide

• tolvaptan

• trabectedin

• warfarin

WHAT ARE THE SIDE EFFECTS OF THIS MEDICATION?

Possible side effects include:

• constipation

• decreased sexual ability

• difficulty sleeping

• dizziness

• headache

• nausea

• nightmares

• stomach pain

• breast enlargement

• confusion

• hives

• itching

• numbness, tingling, weakness, or pain in the hands or feet

• persistent cough, with or without shortness of breath

• poor memory

• signs of clotting problems (e.g., unusual nosebleeds, bruising, blood in urine, coughing blood, bleeding gums, cuts that don't stop bleeding)

• signs of depression (e.g., poor concentration, changes in weight, changes in sleep, decreased interest in activities, thoughts of suicide)

• skin rash

• symptoms of high blood sugar (e.g., frequent urination, increased thirst, excessive eating, unexplained weight loss, poor wound healing, infections, fruity breath odour)

• symptoms of liver damage (such as yellow skin or eyes, abdominal pain, dark urine, clay-coloured stools, loss of appetite, nausea and vomiting, or itching)

• symptoms of muscle damage (unexplained muscle pain, tenderness or weakness, or brown or discoloured urine – especially if you also have a fever or a general feeling of being unwell)

• weakness

© 2023 Arcedpharmas is the registered trademark used under license from YYOUNG Trademark Ltd. All material copyright MediResource Inc. 1996 – 2023. Terms and conditions of use. The contents herein are for informational purposes only. Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. Source: www.medbroadcast.com/drug/getdrug/ACT-Rosuvastatin

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