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RUPALL 10MG BSLPK 30 TB

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RUPALL 10MG (30 TAB)

Generic Name: rupatadine
Brand Name: Rupall
Drug class: antihistamines



WHAT IS THE DOSAGE OF THIS MEDICATION?

Rupatadine is available in the strength of 10 mg tablets and 14 mg/ml/120 ml oral solution.


WHAT IS THIS MEDICATION USED FOR?

Rupatadine, a second-generation antihistamine belonging to the class histamine receptor antagonists, is used for the relief of symptoms associated with seasonal allergic rhinitis (hay fever), perennial allergic rhinitis (year-round allergies), and chronic spontaneous urticaria in adults and children over 12 years. These symptoms include sneezing; runny nose; itchy nose or throat; and tearing and redness of the eyes. It is also used for the relief of symptoms associated with allergic skin conditions, including chronic hives, itching, and other skin disorders. The main difference between first-generation and second-generation antihistamines is that the latter do not cause sleepiness and are considered safer because they interact better with other medications.

Rupatadine works to treat the symptoms of allergic responses by blocking the release of one of the body's natural chemicals known as histamine. Histamine is a chemical created by your immune system to counteract allergens in the body and is responsible for many of the symptoms of an allergic reaction. Histamine causes vessels to swell and dilate, leading to allergy symptoms.

Rupatadine usually starts working within 2 hours and lasts for 24 hours.

The recommended dose of rupatadine for adults and adolescents 12 years of age and older is 10 mg taken by mouth once daily.

The dose for children 2 to 11 years old is based on body weight. Children weighing 10 kg to 25 kg should be given 2.5 mg (2.5 mL) taken by mouth once daily. Children weighing more than 25 kg should take 5 mg (5 mL) by mouth once daily.

Use an oral syringe to measure each dose of the liquid, as it gives a more accurate measurement than household teaspoons. Wash the syringe after each use.

This medication may be taken with food or on an empty stomach.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

It is important to take this medication exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store this medication at room temperature, protect it from light and moisture, and keep it out of the reach of children. Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.


WHO SHOULD NOT TAKE THIS MEDICATION

Do not take rupatadine if you:

  • are allergic to rupatadine or any ingredients of the medication

  • is younger than 12 years of age

  • are taking other certain other medications that are broken down in the liver, including but not limited to:

    • ketoconazole, itraconazole

    • erythromycin

    • diltiazem

    • "statin" medications to lower cholesterol

  • have a history of irregular heart beat including QT prolongation, torsade de pointes, or other arrhythmia

  • have hereditary problems of galactose intolerance, the Lapp lactase deficiency, or glucose-galactose malabsorption (tablets contain lactose)

  • have hereditary problems of fructose intolerance, glucose-galactose malabsorption, or sucrose-isomaltase insufficiency (oral solution contains sucrose)


POTENTIAL INTERACTION WITH OTHER MEDICATION

Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.

Inform your doctor about all prescription, over-the-counter (non-prescription), and herbal medications that you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.

The following medications could potentially interact with rupatadine:

  • aclidinium

  • alcohol

  • amantadine

  • amiodarone

  • antipsychotics (e.g., chlorpromazine, clozapine, haloperidol, olanzapine, quetiapine, risperidone)

  • "azole" antifungals (e.g., itraconazole, ketoconazole, voriconazole)

  • barbiturates (e.g., butalbital, phenobarbital)

  • benzodiazepines (e.g., alprazolam, diazepam, lorazepam)

  • benztropine

  • betahistine

  • buprenorphine

  • butorphanol

  • cannabis

  • chloral hydrate

  • clidinium

  • clonidine

  • cobicistat

  • darifenacin

  • diltiazem

  • dimenhydrinate

  • diphenoxylate

  • disopyramide

  • domperidone

  • donepezil

  • efavirenz

  • eluxadoline

  • entacapone

  • esketamine

  • everolimus

  • fesoterodine

  • gabapentin

  • galantamine

  • glucagon

  • glycopyrrolate

  • grapefruit juice

  • guanfacine

  • HIV protease inhibitors (e.g., atazanavir, indinavir, ritonavir, saquinavir)

  • ipratropium

  • kava kava

  • lamotrigine

  • letermovir

  • levetiracetam

  • macrolide antibiotics (e.g., azithromycin, clarithromycin, erythromycin)

  • maprotiline

  • methadone

  • metoclopramide

  • mifepristone

  • moclobemide

  • muscle relaxants (e.g., cyclobenzaprine, orphenadrine, methocarbamol, tizanidine)

  • nabilone

  • narcotic pain relievers (e.g., codeine, fentanyl, hydromorphone, morphine, oxycodone)

  • nitroglycerin

  • other antihistamines (e.g., azelastine, bilastine, cetirizine, doxylamine, diphenhydramine, hydroxyzine, loratadine)

  • oxybutynin

  • pizotifen

  • pomalidomide

  • potassium chloride

  • pramipexole

  • pregabalin

  • primidone

  • procainamide

  • prochlorperazine

  • protein kinase inhibitors (e.g., ceritinib, idelalisib, imatinib, nilotinib)

  • quinidine

  • rivastigmine

  • ropinirole

  • rotigotine

  • scopolamine

  • sirolimus

  • "statin" anti-cholesterol medications (e.g., atorvastatin, lovastatin, simvastatin)

  • tacrolimus

  • tetrabenazine

  • thiazide diuretics (water pills; e.g., hydrochlorothiazide, indapamide)

  • tiotropium

  • trazodone

  • tricyclic antidepressants (e.g., amitriptyline, nortriptyline, trimipramine)

  • trospium

  • umeclidinium

  • valerian

  • verapamil

  • zolpidem

  • zopiclone


WHAT ARE THE SIDE EFFECTS OF THIS MEDICATION?

Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.

Inform your doctor about all prescription, over-the-counter (non-prescription), and herbal medications that you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.

This is not a complete list of possible side effects. If you notice other effects not listed, please contact your doctor or pharmacist.

Possible side effects include:

  • sleepiness

  • headache

  • dizziness

  • dry mouth

  • sensation of weakness

  • fatigue

  • nausea

  • pain in the upper or lower abdomen (belly)

  • abnormal blood test results (increase in enzyme called creatine phosphokinase)

  • symptoms of the common cold and/or flu; red eyes

  • vomiting and diarrhea

  • mucus in the back of the nose, throat or sinuses

  • throat pain, tonsil pain, pain when swallowing

  • cough

  • pain during menstruation

  • muscle pain and/or muscle weakness

  • menstrual pain

  • red eyes


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